*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : GZ1260000 CHEMICAL NAME : Cyclopropanecarboxylic acid, 3-(2,2-dichlorovinyl)-2,2-dimethyl-, (3-phenoxyphenyl) methyl ester, (1R-trans)- CAS REGISTRY NUMBER : 51877-74-8 LAST UPDATED : 199612 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C21-H20-Cl2-O3 MOLECULAR WEIGHT : 391.31 WISWESSER LINE NOTATION : L3TJ A1 A1 BVO1R COR&& C1UYGG COMPOUND DESCRIPTOR : Agricultural Chemical Tumorigen SYNONYMS/TRADE NAMES : * Biopermethrin * NRDC 147 * (+)-trans-Permethrin * (1R)-trans-Permethrin * RU 22090 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >270 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - rigidity (including catalepsy) Behavioral - aggression REFERENCE : ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 45,325,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3100 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - excitement Behavioral - ataxia REFERENCE : EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 14,15,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Behavioral - excitement Behavioral - ataxia Gastrointestinal - changes in structure or function of salivary glands REFERENCE : EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 21,285,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Amphibian - frog DOSE/DURATION : 7500 ug/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - excitement Behavioral - ataxia REFERENCE : PCBPBS Pesticide Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1971- Volume(issue)/page/year: 20,217,1983 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 *** END OF RECORD ***