*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GZ1260000
CHEMICAL NAME           : Cyclopropanecarboxylic acid,
                          3-(2,2-dichlorovinyl)-2,2-dimethyl-,
                          (3-phenoxyphenyl) methyl ester, (1R-trans)-
CAS REGISTRY NUMBER     : 51877-74-8
LAST UPDATED            : 199612
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C21-H20-Cl2-O3
MOLECULAR WEIGHT        : 391.31
WISWESSER LINE NOTATION : L3TJ A1 A1 BVO1R COR&& C1UYGG
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Tumorigen
SYNONYMS/TRADE NAMES :
   * Biopermethrin
   * NRDC 147
   * (+)-trans-Permethrin
   * (1R)-trans-Permethrin
   * RU 22090
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >270 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - rigidity (including catalepsy)
   Behavioral - aggression
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   45,325,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3100 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - excitement
   Behavioral - ataxia
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 14,15,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - ataxia
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 21,285,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 7500 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - excitement
   Behavioral - ataxia
REFERENCE :
   PCBPBS Pesticide Biochemistry and Physiology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1971-  Volume(issue)/page/year:
   20,217,1983

                              *** REVIEWS ***
 
   IARC Cancer Review:Animal Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 53,329,1991

   IARC Cancer Review:Human No Available Data
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 53,329,1991

   IARC Cancer Review:Group 3
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 53,329,1991

 
                            *** END OF RECORD ***