*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HA6290000
CHEMICAL NAME           : Cytovaricin,
                          12-de((2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranos
                          yl)oxy)-
CAS REGISTRY NUMBER     : 119313-46-1
LAST UPDATED            : 199312
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C40-H68-O12
MOLECULAR WEIGHT        : 741.08
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * 12-De((2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)cytovaricin
   * Phthoramycin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 41,1910,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 41,1910,1988
 
                            *** END OF RECORD ***