*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : HJ8040000 CHEMICAL NAME : P,P-Diamidoimidodiphosphoric acid, N''-ethyl-N,N,N',N'-tetramethyl-, diethyl ester CAS REGISTRY NUMBER : 59740-64-6 BEILSTEIN REFERENCE NO. : 1714933 REFERENCE : 4-04-00-00435 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C10-H27-N3-O4-P2 MOLECULAR WEIGHT : 315.34 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * N''-Ethyl-N,N,N',N'-tetramethyl-P,P-diamidoimidodiphosphoric acid diethyl ester * Phosphoramidic acid, (bis(dimethylamino)phosphinyl)ethyl-, diethyl ester *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 105 mg/kg TOXIC EFFECTS : Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea REFERENCE : PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,136,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 109 mg/kg TOXIC EFFECTS : Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea REFERENCE : PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,136,1957 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,136,1957 *** END OF RECORD ***