*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CB9225000
CHEMICAL NAME           : Dianemycin,
                          10-demethyl-19-de((tetrahydro-5-methoxy-6-methyl-2H-p
                          yran-2-yl)oxy)-12-met hyl-11-
                          O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-,
                          monosodium salt, (11(2R,5S,6R),12R)-
CAS REGISTRY NUMBER     : 58399-44-3
OTHER CAS REGISTRY NOS. : 58339-29-0
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C47-H77-O13.Na
MOLECULAR WEIGHT        : 873.23
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic A-130, sodium salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 28,931,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 28,931,1975
 
                            *** END OF RECORD ***