*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HM0337000
CHEMICAL NAME           : 2,7b-Diazabenzo(f)cycloprop(cd)indene-4,7-dione,
                          1,2,2a,3,7c,7d-hexahydro-3-(((aminocarbonyl)
                          oxy)methyl)-2a,5-dimethoxy-6-methyl-,
                          (2aR-(2a-alpha,3-alpha,7c-alpha,7d-alpha))-
CAS REGISTRY NUMBER     : 91917-64-5
LAST UPDATED            : 198909
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H19-N3-O6
MOLECULAR WEIGHT        : 349.38
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AX 2
   * AX 2 (neoplasm inhibitor)
   * Isomitomycin A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 27 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTKRDX Gan to Kagaku Ryoho.  Cancer and Chemotherapy.  (1-8-9 Yaesu,
   Chuo-ku, Tokyo 103, Japan) V.1-    1974-  Volume(issue)/page/year:
   15,369,1988
 
                            *** END OF RECORD ***