*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HM0353490
CHEMICAL NAME           : 3,7-Diazabicyclo(3.3.1)nonane-3-thiocarboxamide,
                          N-benzyl-5-methyl-9-oxo-2,4,6,8- tetraphenyl-
CAS REGISTRY NUMBER     : 82058-38-6
BEILSTEIN REFERENCE NO. : 5686329
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C40-H37-N3-O-S
MOLECULAR WEIGHT        : 607.86
WISWESSER LINE NOTATION : T66 A AV DN HNTJ CR& DYUS&M1R& ER& GR& H1 IR
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   N-Benzyl-5-methyl-9-oxo-2,4,6,8-tetraphenyl-3,7-diazabicyclo(3.3.1)nonan
     e-3-thiocarboxamide
   * ITA 441
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
   Behavioral - muscle weakness
   Behavioral - antianxiety
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,187,1982
 
                            *** END OF RECORD ***