*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HM2862000
CHEMICAL NAME           : 7,9-Diazaspiro(4.5)decane-6,8,10-trione,
                          1,2-dimethyl-4-ethyl-8-thioxo-, sodium salt
CAS REGISTRY NUMBER     : 63990-27-2
LAST UPDATED            : 199109
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C12-H18-N2-O2-S.Na
MOLECULAR WEIGHT        : 277.37
WISWESSER LINE NOTATION : T6MVXVMYJ FUS C-& AL5XTJ B1 C1 E2 &-NA-
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Sodium  
   1,2-dimethyl-4-ethyl-8-thioxo-7,9-diazaspiro(4.5)decane-6,8,10-trione
   * Sodium  
   spiro(2',3'-dimethyl-5'-ethylcyclopentane)-5,5-pyrimidine-2-thio-4,6-dio  
   ne
   * Sodium spiro(2,3-dimethyl-5-ethylcyclopentane 2'-thiobarbiturate)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 83 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRAAA7 Current Researches in Anesthesia and Analgesia.  (Cleveland, OH)
   V.1-35, 1922-56.  For publisher information, see AACRAT.
   Volume(issue)/page/year: 29,89,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 63 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRAAA7 Current Researches in Anesthesia and Analgesia.  (Cleveland, OH)
   V.1-35, 1922-56.  For publisher information, see AACRAT.
   Volume(issue)/page/year: 29,89,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 42 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRAAA7 Current Researches in Anesthesia and Analgesia.  (Cleveland, OH)
   V.1-35, 1922-56.  For publisher information, see AACRAT.
   Volume(issue)/page/year: 29,89,1950
 
                            *** END OF RECORD ***