*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HM2967000
CHEMICAL NAME           : Diazene, bis(1-methylethyl)-, 1-oxide
CAS REGISTRY NUMBER     : 17697-53-9
LAST UPDATED            : 199009
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H14-N2-O
MOLECULAR WEIGHT        : 130.22
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Azoxyisopropane
   * 2-Azoxypropane
   * Bis(1-methylethyl)diazene 1-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 773 mg/kg/26W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 8,1947,1987
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 1 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 221,263,1989
 
                            *** END OF RECORD ***