*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : HM3658000
CHEMICAL NAME : 1H-1,3-Diazepine-4-carboxylic acid,
hexahydro-2-imino-, methyl ester, monohydrochloride,
(-)-
CAS REGISTRY NUMBER : 26281-34-5
LAST UPDATED : 199112
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C7-H13-N3-O2.Cl-H
MOLECULAR WEIGHT : 207.69
WISWESSER LINE NOTATION : T7MYMTJ BUM DVO1 &GH
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* (-)-Hexahydro-2-imino-1H-1,3-diazepine-4-carboxylic acid methyl ester
hydrochloride
* OH 41
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 185,159,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 68 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
Autonomic Nervous System - ganglion facilitant
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 189,408,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 7800 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 185,159,1970
*** END OF RECORD ***