*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HM3870000
CHEMICAL NAME           : 1H-1,4-Diazepine, hexahydro-,
                          1,4-bis(2-(2-pyridyl)ethyl)-
CAS REGISTRY NUMBER     : 14549-76-9
BEILSTEIN REFERENCE NO. : 0548520
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H26-N4
MOLECULAR WEIGHT        : 310.49
WISWESSER LINE NOTATION : T7N DNTJ A2- BT6NJ& D2- BT6NJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,4-Bis(beta-2-pyridylethyl)-hexahydro-1H-1,4-diazepine
   * Bis-1,4-(beta-2-pyridylethyl)homopiperazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,812,1967
 
                            *** END OF RECORD ***