*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HO0565010
CHEMICAL NAME           : 5H-Dibenz(b,f)azepine,
                          10,11-dihydro-5-(o-(morpholinomethyl)benzoyl)-,
                          hydrochloride
LAST UPDATED            : 198405
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C26-H26-N2-O2.Cl-H
MOLECULAR WEIGHT        : 435.00
WISWESSER LINE NOTATION : T C676 BN&T&J BVR B1- AT6N DOTJ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-(o-(Morpholinomethyl)benzoyl)-10,11-dihydro-5H-dibenz(b,f)azepine  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 217 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - antipsychotic
REFERENCE :
   ARPMAS Archiv der Pharmazie (Weinheim, Germany)  (VCH Pub., Inc., 303 NW
   12th Ave., Deerfield Beach, FL 33441)  V.51-261, 1835-1923; V.305-    1972-
   Volume(issue)/page/year: 316,1018,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1749 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - antipsychotic
REFERENCE :
   ARPMAS Archiv der Pharmazie (Weinheim, Germany)  (VCH Pub., Inc., 303 NW
   12th Ave., Deerfield Beach, FL 33441)  V.51-261, 1835-1923; V.305-    1972-
   Volume(issue)/page/year: 316,1018,1983
 
                            *** END OF RECORD ***