*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HO1700000
CHEMICAL NAME           : 5H-Dibenz(b,f)azepine,
                          5-(3-(dimethylamino)propyl)-10,11-dihydro-, and
                          2-((p-chlorobenzyl)
                          (2-(dimethylamino)ethyl)amino)pyridine (1:1)
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H24-N2.C16-H20-Cl-N3
MOLECULAR WEIGHT        : 570.29
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
                          Human
SYNONYMS/TRADE NAMES :
   * Chloropyramine and imipramine (1:1)
   * Imipramine and chloropyramine (1:1)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE                    : 108 mg/kg
SEX/DURATION            : female 1-90 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
REFERENCE :
   LANCAO Lancet.  (7 Adam St., London WC2N 6AD, UK)  V.1-    1823-
   Volume(issue)/page/year: 2,282,1973
 
                            *** END OF RECORD ***