*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : HO2100000
CHEMICAL NAME : 5H-Dibenz(b,f)azepine,
5-(3-(dimethylamino)propyl)-10,11-dihydro-, 5-oxide
CAS REGISTRY NUMBER : 2207-85-4
BEILSTEIN REFERENCE NO. : 1653950
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C19-H24-N2-O
MOLECULAR WEIGHT : 296.45
WISWESSER LINE NOTATION : T C676 BK&T&J BO B3N1&1
SYNONYMS/TRADE NAMES :
* 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)propyl)-,
5-oxide
* GP 38383
* Imipramine N-oxide
* IPNO
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 102 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland)
V.12-17, 1965-67. For publisher information, see PHMGBN.
Volume(issue)/page/year: 15,187,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,79,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,79,1972
*** END OF RECORD ***