*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : HM1157000
CHEMICAL NAME : 3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane,
3,12-bis(3-bromo-1-oxopropyl)-, dichloride
CAS REGISTRY NUMBER : 86641-76-1
LAST UPDATED : 198809
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C18-H32-Br2-N4-O2.2Cl
MOLECULAR WEIGHT : 567.26
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 3,12-Bis(3-bromo-1-oxopropyl)-3,12-diaza-6,9-diazoniadispiro(5.2.5.2)hex
adecane dichloride
* N,N'''-Di(beta-bromopropionyl)-N',N''-dispirotripiperazinium dichloride
* N,N(sup 3)-Di(beta-bromopropionyl)-N(sup 1),N(sup
2)-dispirotripiperazinium dichloride
* Spirobromin
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 800 mg/kg
TOXIC EFFECTS :
Behavioral - tremor
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
9,121,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 825 mg/kg
TOXIC EFFECTS :
Behavioral - tremor
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
9,121,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1924 mg/kg
TOXIC EFFECTS :
Behavioral - tremor
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
9,121,1984
*** END OF RECORD ***