*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HO7643000
CHEMICAL NAME           : 5H-Dibenzo(a,d)cyclohepten-10-carbonitrile,
                          5-(3-alpha-tropanyloxy)-, hydrogen fumarate
CAS REGISTRY NUMBER     : 27719-95-5
LAST UPDATED            : 199012
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H23-N2-O.C4-H4-O4
MOLECULAR WEIGHT        : 471.57
WISWESSER LINE NOTATION : L C676 BHJ ICN BO- GT56 A ANTJ A1 &QV1U1VQ -T
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-((10-Cyano-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-tropane hydrogen  
   fumarate
   * 5-(3-alpha-Tropanyloxy)-5H-dibenzo(a,d)cyclohepten-10-carbonitrile  
   hydrogen fumarate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 420 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
   Behavioral - changes in motor activity (specific assay)
   Behavioral - analgesia
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 19,1936,1969
 
                            *** END OF RECORD ***