*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HO8925000
CHEMICAL NAME           : 5H-Dibenzo(a,d)cycloheptene-delta(sup
                          5),gamma-propylamine, 3-chloro-10,11-dihydro-N,N-
                          dimethyl-, monohydrochloride
CAS REGISTRY NUMBER     : 2047-30-5
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H22-Cl-N.Cl-H
MOLECULAR WEIGHT        : 348.34
WISWESSER LINE NOTATION : L C676 BYJ BU3N1&1 EG &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Chloroamitriptyline hydrochloride
   * Chlorproheptadien
   * Chlorproheptadiene hydrochlroide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 144,481,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 43 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 144,481,1963
 
                            *** END OF RECORD ***