*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HP3325000
CHEMICAL NAME           : Dibenzo-p-dioxin, 1-nitro-2,3,7,8-tetrachloro-
CAS REGISTRY NUMBER     : 62782-12-1
LAST UPDATED            : 199303
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H3-Cl4-N-O4
MOLECULAR WEIGHT        : 366.96
WISWESSER LINE NOTATION : T C666 BO IOJ DNW EG FG LG MG
SYNONYMS/TRADE NAMES :
   * 1-Nitro-2,3,7,8-tetrachlorodibenzo-p-dioxin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 mg/kg
TOXIC EFFECTS :
   Endocrine - changes in spleen weight
   Endocrine - changes in thymus weight
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   44,335,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 47500 ng/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   44,335,1978
 
                            *** END OF RECORD ***