*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : HP6475000 CHEMICAL NAME : Dibenzo(a,h)phenazine CAS REGISTRY NUMBER : 226-47-1 BEILSTEIN REFERENCE NO. : 0217195 REFERENCE : 5-23-10-00184 (Beilstein Handbook Reference) LAST UPDATED : 199803 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C20-H12-N2 MOLECULAR WEIGHT : 280.34 WISWESSER LINE NOTATION : T G6 D6 B666 CN NNJ COMPOUND DESCRIPTOR : Tumorigen Mutagen SYNONYMS/TRADE NAMES : * 7,14-Diazadibenz(a,h)anthracene * 1,2,5,6-Dibenzophenazine * Dibenz(a,h)phenazine * 1,2:5,6-Dibenzphenazine *** HEALTH HAZARD DATA *** ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7 mg/kg TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors REFERENCE : COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 240,1738,1955 TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Implant SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application REFERENCE : NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 25,641,1978 ** MUTATION DATA ** TYPE OF TEST : Specific locus test ROUTE OF EXPOSURE : Oral TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 1800 umol/L REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 30,195,1970 *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster Sex-linked lethal *** END OF RECORD ***