*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HQ1800000
CHEMICAL NAME           : Dibenzo(a,g)quinolizinium,
                          5,6-dihydro-2,3,9,10-tetramethoxy-, hydroxide
CAS REGISTRY NUMBER     : 131-04-4
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H22-N-O4.H-O
MOLECULAR WEIGHT        : 369.45
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Calystigine
   * 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo(a,g)quinolizinium hydroxide
   * Palmatine hydroxide
   * Palmatinium hydroxide
   * 7,8,13,13a-Tetradehydro-2,3,9,10-tetramethoxyberbinium hydroxide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE                    : 1800 mg/kg
SEX/DURATION            : male 60 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
   Reproductive - Paternal Effects - other effects on male
REFERENCE :
   JOETD7 Journal of Ethnopharmacology.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1979-  Volume(issue)/page/year:
   25,151,1989
 
                            *** END OF RECORD ***