*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HP1760000
CHEMICAL NAME           : 5H-Dibenzo(b,e)(1,4)diazepine,
                          8-chloro-11-(4-methyl-1-piperazinyl)-, N-oxide
CAS REGISTRY NUMBER     : 34233-69-7
LAST UPDATED            : 198706
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H19-Cl-N4-O
MOLECULAR WEIGHT        : 342.86
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine  
   N-oxide
   * Clozapine N-oxide
   * VUFB-12426
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 245 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 43,309,1978
 
                            *** END OF RECORD ***