*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HQ2551000
CHEMICAL NAME           : Dibenzo(b,f)thiepin,
                          10,11-dihydro-8-chloro-(R)-10-((R)-3'-methylethylamin
                          opyrrolidino)-
CAS REGISTRY NUMBER     : 57602-87-6
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H27-Cl3-N2-S
MOLECULAR WEIGHT        : 445.91
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   8-Chloro-(R)-10-((R)-3'-methylethylaminopyrrolidino)-10,11-dihydrodibenz
     o(b,f)thiepin
   * Dibenzo(b,f)thiepin,  
   8-chloro-(R)-10-((R)-3'-methylethylaminopyrrolidino)-10,11-dihydro-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 186 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 19,40,1976
 
                            *** END OF RECORD ***