*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HQ2634000
CHEMICAL NAME           : Dibenzo(b,f)thiepin,
                          7-(2-(dimethylamino)ethoxy)-11-ethyl-10-phenyl-
CAS REGISTRY NUMBER     : 85850-77-7
BEILSTEIN REFERENCE NO. : 5623397
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C26-H27-N-O-S
MOLECULAR WEIGHT        : 401.60
WISWESSER LINE NOTATION : T C676 BSJ EO2N1&1 IR& J2
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 7-(2-(Dimethylamino)ethoxy)-11-ethyl-10-phenyldibenzo(b,f)thiepin
   * Ethylamine,  
   N,N-dimethyl-2-((10-ethyl-11-phenyldibenzo(b,f)thiepin-3-yl)oxy)-
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 mg/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,1131,1983
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 15 mg/kg
SEX/DURATION            : female 3 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,1131,1983
 
                            *** END OF RECORD ***