*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : HZ1800000 CHEMICAL NAME : Diesel fuels CAS REGISTRY NUMBER : 68334-30-5 OTHER CAS REGISTRY NOS. : 68512-90-3 LAST UPDATED : 199710 DATA ITEMS CITED : 13 COMPOUND DESCRIPTOR : Tumorigen Primary Irritant SYNONYMS/TRADE NAMES : * Automotive diesel oil * Diesel oil (petroleum) * Diesel oils * Diesel test fuel * Fuels, diesel * Olej napedowy III *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 uL/24H REACTION SEVERITY : Severe REFERENCE : ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,29,1990 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AETODY Advances in Modern Environmental Toxicology. (Senate Press, Inc., P.O. Box 252, Princeton Junction, NJ 08550) V.1- 1980- Volume(issue)/page/year: 6,1,1984 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >5 mL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,29,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 400 ug/m3/16H/2.5Y-I TOXIC EFFECTS : Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases REFERENCE : JIDOAA Experimental Animals. Jikken Dobutso Iho. (Nippon Jikken Dobutsu Gakkai, c/o Keio Gijuku Daigaku Igakubu Jikken Dobutsu Senta, 35 Shinano-machi, Shinjuku-ku, Tokyo 160, Japan) V.1- 1952- Volume(issue)/page/year: 39,213,1990 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2 gm/m3/6H/3W-I TOXIC EFFECTS : Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Lungs, Thorax, or Respiration - other changes Blood - changes in erythrocyte (RBC) count REFERENCE : JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 7,265,1987 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 80 mL/kg/12D-C TOXIC EFFECTS : Liver - other changes Kidney, Ureter, Bladder - other changes Related to Chronic Data - death REFERENCE : 52MLA2 "Toxicology of Petroleum Hydrocarbons, Proceedings of the Symposium, 1st, 1982," MacFarland, H.N., et al., eds., Washington, DC, American Petroleum Institute, 1983 Volume(issue)/page/year: 1,1,1983 *** REVIEWS *** IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 45,219,1989 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 45,219,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - Y1022 No. of Facilities: 3364 (estimated) No. of Industries: 20 No. of Occupations: 25 No. of Employees: 111267 (estimated) No. of Female Employees: 20396 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - Y1025 No. of Facilities: 112 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 4771 (estimated) No. of Female Employees: 156 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA Section 8(d) unpublished health/safety studies EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 *** END OF RECORD ***