*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : IA2400000
CHEMICAL NAME           : Diethylamine, 2,2'-dichloro-N-nitroso-
CAS REGISTRY NUMBER     : 67856-68-2
BEILSTEIN REFERENCE NO. : 1762838
REFERENCE               : 3-04-00-00246 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C4-H8-Cl2-N2-O
MOLECULAR WEIGHT        : 171.04
WISWESSER LINE NOTATION : ONN2G2G
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Bis(2-chloroethyl)nitrosoamine
   * Nitrosobis(2-chloroethyl)amine
   * N-Nitroso-2,2'-dichlorodiethylamine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 345 mg/kg/30W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
   Gastrointestinal - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   38,2391,1978
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 66,1,1979
 
                            *** END OF RECORD ***