*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AM1300000
CHEMICAL NAME           : Acetonitrile, 2,2'-(N-nitrosoimino)di-
CAS REGISTRY NUMBER     : 16339-18-7
BEILSTEIN REFERENCE NO. : 1761607
REFERENCE               : 1-04-00-00487 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C4-H4-N4-O
MOLECULAR WEIGHT        : 124.12
WISWESSER LINE NOTATION : NC1NNO&1CN
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Acetonitrile, nitrosiminodi-
   * Acetonitrile, 2,2'-(nitrosoimino)bis-
   * N-Nitrosamino diacetonitril
   * Nitrosiminodiacetonitrile
   * N-Nitrosodiacetonitrile
   * N-Nitrosodi(cyanomethyl)amine
   * 2,2'-(Nitrosoimino)bisacetonitrile
   * 2,2'-(N-Nitrosoimino)diacetonitrile
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 163 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   69,103,1967
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1584 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   69,103,1967
 
                            *** END OF RECORD ***