*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AL0875000
CHEMICAL NAME           : Acetohydroxamic acid, N-(2-naphthyl)-
CAS REGISTRY NUMBER     : 2508-23-8
BEILSTEIN REFERENCE NO. : 2725217
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C12-H11-N-O2
MOLECULAR WEIGHT        : 201.24
WISWESSER LINE NOTATION : L66J CNQV1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acetamide, N-hydroxy-N-2-naphthalenyl-
   * N-Acetyl-N-hydroxy-2-aminonaphthalene
   * N-Acetyl-2-naphthylhydroxylamine
   * 2-(N-Hydroxyacetamido)naphthalene
   * N-Hydroxy-2-acetylaminonaphthalene
   * N-Hydroxy-N-2-naphthalenylacetamide
   * N-2-Naphthylacetohydroxamic acid
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Tumorigenic - facilitates action of known carcinogen
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 108,924,1963
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 nmol/plate
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   67,215,1988
 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 10 umol/L
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 72,847,1984

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   AEHLAU Archives of Environmental Health.  (Heldref Pub., 4000 Albemarle St.,
   NW, Washington, DC 20016)  V.1-    1960-  Volume(issue)/page/year: 23,6,1971

 
                            *** END OF RECORD ***