*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AM5400000
CHEMICAL NAME           : Acetophenone, 4'-(amidinoguanidino)-,
                          amidinohydrazone, dihydrochloride
LAST UPDATED            : 198612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H17-N9.2Cl-H
MOLECULAR WEIGHT        : 348.29
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4'-(Amidinoguanidino)acetophenone amidinohydrazone dihydrochloride
   * p-Biguanidoacetophenone amidinohydrazone dihydrochloride
   * Ciba 23889-Ba dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 19,324,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 19,324,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 19,324,1962
 
                            *** END OF RECORD ***