*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AM5500000
CHEMICAL NAME           : Acetophenone, p-amino-
CAS REGISTRY NUMBER     : 99-92-3
BEILSTEIN REFERENCE NO. : 0471493
REFERENCE               : 4-14-00-00100 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C8-H9-N-O
MOLECULAR WEIGHT        : 135.18
WISWESSER LINE NOTATION : ZR DV1
COMPOUND DESCRIPTOR     : Agricultural Chemical
SYNONYMS/TRADE NAMES :
   * Acetophenone, 4'-amino-
   * p-Acetylaniline
   * 4-Acetylaniline
   * p-Aminoacetofenonu
   * p-Aminoacetophenone
   * 4'-Aminoacetophenone
   * p-Aminoacetylbenzene
   * 1-(4-Aminophenyl)ethanone
   * Ethanone, 1-(4-aminophenyl)-
   * USAF EK-631
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 381 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GEPHDP General Pharmacology.  (Pergamon Press Inc., Maxwell House, Fairview
   Park, Elmsford, NY 10523) V.6-    1975-  Volume(issue)/page/year:
   14,465,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 260 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 80,31,1944
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 596 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GEPHDP General Pharmacology.  (Pergamon Press Inc., Maxwell House, Fairview
   Park, Elmsford, NY 10523) V.6-    1975-  Volume(issue)/page/year:
   14,465,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >70 mg/kg
TOXIC EFFECTS :
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 80,31,1944
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 133 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***