*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AM5800000 CHEMICAL NAME : Acetophenone, 3'-amino- CAS REGISTRY NUMBER : 99-03-6 BEILSTEIN REFERENCE NO. : 0386009 REFERENCE : 4-14-00-00096 (Beilstein Handbook Reference) LAST UPDATED : 199806 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C8-H9-N-O MOLECULAR WEIGHT : 135.18 WISWESSER LINE NOTATION : ZR CV1 COMPOUND DESCRIPTOR : Mutagen Primary Irritant SYNONYMS/TRADE NAMES : * Acetophenone, m-amino- * m-Acetylaniline * 3-Acetylaniline * 3-Aminoacetofenon * beta-Aminoacetophenone * m-Aminoacetophenone * 3'-Aminoacetophenone * m-Aminoacetylbenzene * 1-(3-Aminophenyl)ethanone * Ethanone, 1-(3-aminophenyl)- *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg/24H REACTION SEVERITY : Mild REFERENCE : 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,730,1986 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1870 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2048 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 2,55,1950 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 4340 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 10 mg/L REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5,803,1983 TYPE OF TEST : Cytogenetic analysis ROUTE OF EXPOSURE : Subcutaneous TEST SYSTEM : Rodent - mouse DOSE/DURATION : 400 mg/kg REFERENCE : TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 2,538,1968 *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***