*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AM8050000
CHEMICAL NAME           : Acetophenone, 3',4'-dihydroxy-2-(methylamino)-
CAS REGISTRY NUMBER     : 99-45-6
BEILSTEIN REFERENCE NO. : 2366101
REFERENCE               : 4-14-00-00832 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C9-H11-N-O3
MOLECULAR WEIGHT        : 181.21
WISWESSER LINE NOTATION : QR BQ DV1M1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Adrenalone
   * Adrenon
   * Adrenone
   * Chemosan
   * 3,4-Dihydroxy-alpha-methylaminoacetophenone
   * 3',4'-Dihydroxy-2-(methylamino)acetophenone
   * 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone
   * Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-
   * Haemodan
   * Kephrine
   * Ketogaze
   * Methaminoacetocatechol
   * 4-Methylaminoacetocatechol
   * 4-Methylaminoacetopyrocatechol
   * Remestyp
   * Stryphnon
   * Stryphnone
   * Styphnone
   * Stypnon
   * U 2134
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 275 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 226,493,1955
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Autonomic Nervous System - sympathomimetic
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 153,161,1930
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 250 umol/L
REFERENCE :
   ABCHA6 Agricultural and Biological Chemistry.  (Maruzen Co. Ltd., POB 5050,
   Tokyo International, Tokyo 100-31, Japan)  V.25-    1961-
   Volume(issue)/page/year: 42,1019,1978
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Lung
DOSE/DURATION           : 250 umol/L
REFERENCE :
   ABCHA6 Agricultural and Biological Chemistry.  (Maruzen Co. Ltd., POB 5050,
   Tokyo International, Tokyo 100-31, Japan)  V.25-    1961-
   Volume(issue)/page/year: 42,1019,1978
 
                            *** END OF RECORD ***