*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AM8238000
CHEMICAL NAME           : Acetophenone,
                          3',4'-dihydroxy-2-((1,2,3,4-tetrahydro-2-naphthyl)ami
                          no)-, hydrochloride
CAS REGISTRY NUMBER     : 16149-22-7
LAST UPDATED            : 198303
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H19-N-O3.Cl-H
MOLECULAR WEIGHT        : 333.84
WISWESSER LINE NOTATION : L66&TJ HM1VR CQ DQ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3',4'-Dihydroxy-2-((1,2,3,4-tetrahydro-2-naphthyl)amino)acetophenone  
   hydrochloride
   * N-beta-Tetra-hydronaphthyl noradrenalone hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 192,279,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 158 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 192,279,1971
 
                            *** END OF RECORD ***