*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AM8800000
CHEMICAL NAME           : Acetophenone, 4'-hydroxy-3'-methoxy-
CAS REGISTRY NUMBER     : 498-02-2
BEILSTEIN REFERENCE NO. : 0637373
REFERENCE               : 4-08-00-01814 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C9-H10-O3
MOLECULAR WEIGHT        : 166.19
WISWESSER LINE NOTATION : 1VR DQ CO1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acetoguaiacon
   * Acetoguaiacone
   * Acetovanillone
   * Acetovanilone
   * Acetovanyllon
   * Apocynin
   * Apocynine
   * Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-
   * 4'-Hydroxy-3'-methoxyacetophenone
   * 1-(4-Hydroxy-3-methoxyphenyl)ethanone
   * 3-Metoksy-4-hydroksyacetofenon
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCTKAG Bromatologia i Chemia Toksykologiczna.  (Ars Polona, POB 1001, 00-068
   Warsaw 1, Poland) V.4-    1971-  Volume(issue)/page/year: 14,301,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 650 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 7,178,1964
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 400 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 119,273,1983

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***