*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AM9668000
CHEMICAL NAME           : Acetophenone, 2-phenyl-2-(1-pyrrolidinyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 27590-61-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H19-N-O.Cl-H
MOLECULAR WEIGHT        : 301.84
WISWESSER LINE NOTATION : T5NTJ AYR&VR &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Phenyl-2-(1-pyrrolidinyl)-acetophenone hydrochloride
   * (alpha-N-Pyrrolidino-benzyl)phenyl-cetone chlorhydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 199 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMXXAJ French Medicament Patent Document.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Discontinued.
   Volume(issue)/page/year: #2326M
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 12,191,1964
 
                            *** END OF RECORD ***