*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AN3328000
CHEMICAL NAME           : o-Acetotoluidide,
                          6'-chloro-2-(p-chlorobenzyl(2-(pyrrolidinyl)ethyl)ami
                          no)-, dihydrochloride
LAST UPDATED            : 199012
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C22-H27-Cl2-N3-O.2Cl-H
MOLECULAR WEIGHT        : 493.34
WISWESSER LINE NOTATION : T5NTJ A2N1R DG&1VMR BG F1 &GH 2
COMPOUND DESCRIPTOR     : Drug
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * C 5343
   * 6'-Chloro-2-(p-chlorobenzyl(2-(pyrrolidinyl)ethyl)amino)-o-acetotoluidide 
    dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2%
REACTION SEVERITY       : Severe
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 9,167,1959
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 91 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 9,167,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 9,167,1959
 
                            *** END OF RECORD ***