*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AN7701000
CHEMICAL NAME           : 2',6'-Acetoxylidide, 2-(diethylamino)-4'-hydroxy-,
                          hydrochloride
LAST UPDATED            : 198605
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H22-N2-O2.Cl-H
MOLECULAR WEIGHT        : 286.84
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-(Diethylamino)-4'-hydroxy-2',6'-acetoxylidide hydrochloride
   * Hydroxylidocaine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 367 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 111,224,1954
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 279 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 111,224,1954
 
                            *** END OF RECORD ***