*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR5542000
CHEMICAL NAME           : Aconitane-7,8-diol,
                          20-ethyl-4-(((2-(3-methyl-2,5-dioxo-1-pyrrolidinyl)be
                          nzoyl)oxy)methyl)- 1,6,14,16-tetramethoxy-,
                          (1-alpha,4(S),6-beta,14-alpha,16-beta)-
CAS REGISTRY NUMBER     : 21019-30-7
BEILSTEIN REFERENCE NO. : 0076234
REFERENCE               : 4-21-00-04589 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C37-H50-N2-O10
MOLECULAR WEIGHT        : 682.89
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * Delartine
   * Delsemidine
   * Lycaconitine, methyl-
   * Methyllycaconitine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 31800 ug/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1953-  Volume(issue)/page/year: 41,96,1993
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CTYAD8 Zhongcaoyao.  Chinese Traditional and Herbal Medicine.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
      1980-  Volume(issue)/page/year: 15,180,1984
 
                            *** END OF RECORD ***