*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JG6716100
CHEMICAL NAME           : 1,3-Dioxa-6-aza-2-silacyclooctane-6-ethanol,
                          2,2-dimethyl-, diphenylacetate (ester)
CAS REGISTRY NUMBER     : 58647-65-7
BEILSTEIN REFERENCE NO. : 5989082
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H29-N-O4-Si
MOLECULAR WEIGHT        : 399.61
WISWESSER LINE NOTATION : T8O-SI-O FNTJ B1 B1 F2OVYR&R
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acetic acid, diphenyl-, ester with  
   2,2-dimethyl-1,3-dioxa-6-aza-2-silacyclooctane-6-ethanol
   * 2,2-Dimethyl-1,3-dioxa-6-aza-2-silacyclooctane-6-ethanol diphenylacetate  
   (ester)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 16,425,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 16,425,1981
 
                            *** END OF RECORD ***