*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JG6719000
CHEMICAL NAME           : 1,5-Dioxa-9-azaspiro(5.5)undecane,
                          9-(2,6-diamino-4-pyrimidinyl)-, 1'-oxide
CAS REGISTRY NUMBER     : 83540-23-2
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H19-N5-O3
MOLECULAR WEIGHT        : 281.36
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 9-(2,6-Diamino-4-pyrimidinyl)-1,5-dioxa-9-azaspiro(5.5)undecane 1'-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   121,16,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 420 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   121,16,1982
 
                            *** END OF RECORD ***