*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : JH1100000 CHEMICAL NAME : 1,4-Dioxane-2,5-dione, 3,6-dimethyl- CAS REGISTRY NUMBER : 95-96-5 LAST UPDATED : 199712 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C6-H8-O4 MOLECULAR WEIGHT : 144.14 SYNONYMS/TRADE NAMES : * Dilactide * 3,6-Dimethyl-1,4-dioxane-2,5-dione * p-Dioxane-2,5-dione, 3,6-dimethyl- * Lactic acid, bimol. cyclic ester * Lactide *** HEALTH HAZARD DATA *** ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 35 gm/kg/2W-I TOXIC EFFECTS : Gastrointestinal - changes in structure or function of esophagus Gastrointestinal - ulceration or bleeding from stomach Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 36(1, Pt 2),274,1997 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 9100 mg/kg/13W-I TOXIC EFFECTS : Gastrointestinal - ulceration or bleeding from stomach REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 36(1, Pt 2),274,1997 *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***