*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JI4904400
CHEMICAL NAME           : 1,3-Dioxolo(4,5-g)isoquinolinium,
                          7,8-dihydro-4-methoxy-6-p-tolyl-, bromide
LAST UPDATED            : 198806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H18-N-O3.Br
MOLECULAR WEIGHT        : 376.28
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Methoxy-6-p-tolyl-7,8-dihydro-1,3-dioxolo(4,5-g)isoquinolinium bromide
   * N-p-Methyl-phenyl-norcotarnin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   15,111,1960
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   15,111,1960
 
                            *** END OF RECORD ***