*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JI5025000
CHEMICAL NAME           : 7H-(1,3)Dioxolo(4,5-j)pyrrolo(3,2,1-de)phenanthridin-
                          7-one
CAS REGISTRY NUMBER     : 52886-06-3
OTHER CAS REGISTRY NOS. : 58591-64-3
BEILSTEIN REFERENCE NO. : 0249337
REFERENCE               : 4-27-00-06582 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H9-N-O3
MOLECULAR WEIGHT        : 263.26
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 4,5-Etheno-8,9-methylenedioxy-6-phenanthridone
   * Hippadine
   * Pratorine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 45 mg/kg
SEX/DURATION            : male 3 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   PLMEAA Planta Medica.  (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart
   1, Fed. Rep. Ger.) V.1-    1953-  Volume(issue)/page/year: 49,252,1983
 
                            *** END OF RECORD ***