*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : IO0700000 CHEMICAL NAME : 1,4-Dimethanesulfonoxy-2-butyne CAS REGISTRY NUMBER : 2917-96-6 BEILSTEIN REFERENCE NO. : 1878701 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C6-H10-O6-S2 MOLECULAR WEIGHT : 242.28 WISWESSER LINE NOTATION : WS1&O2UU2OSW1 COMPOUND DESCRIPTOR : Tumorigen Mutagen SYNONYMS/TRADE NAMES : * 2-Butyne-1,4-diol, dimethanesulfonate * CB2058 *** HEALTH HAZARD DATA *** ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 320 mg/kg/5W-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 17,64,1957 ** MUTATION DATA ** TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Parenteral TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 10 mmol/L REFERENCE : JOGNAU Journal of Genetics. (Belghoria, India) V.1-63, 1910-77. Discontinued. Volume(issue)/page/year: 54,146,1956 TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Unreported TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 10 mmol/L REFERENCE : ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 160,228,1969 *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Positive: D melanogaster Sex-linked lethal *** END OF RECORD ***