*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JO6300000
CHEMICAL NAME           : 2,6-Dithia-1,3,5,7-tetraazaadamantane,
                          2,2,6,6-tetraoxide
CAS REGISTRY NUMBER     : 80-12-6
BEILSTEIN REFERENCE NO. : 0257816
REFERENCE               : 4-27-00-09647 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C4-H8-N4-O4-S2
MOLECULAR WEIGHT        : 240.28
WISWESSER LINE NOTATION : T66 B6 A B- C 1B I ASWN DNSWN HNTJ
COMPOUND DESCRIPTOR     : Agricultural Chemical
SYNONYMS/TRADE NAMES :
   * 2,6-Dithia-1,3,5,7-tetrazatricyclo(3.3.1.1(sup  
   3,7))decane-2,2,6,6-tetraoxide
   * NSC 172824
   * Tetramethylenedisulfotetramine
   * Tetramethylenedisulphotetramine
   * Tetramine (adamantane derivative)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4850 mg/kg
TOXIC EFFECTS :
   Spinal Cord - other degenerative changes
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 46,239,1957
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DMWOAX Deutsche Medizinische Wochenschrift.  (Stuttgart, Fed. Rep. Ger.)
   V.1-104, 1875-1979.  Volume(issue)/page/year: 75,183,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 50,858,1961
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DMWOAX Deutsche Medizinische Wochenschrift.  (Stuttgart, Fed. Rep. Ger.)
   V.1-104, 1875-1979.  Volume(issue)/page/year: 75,183,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,1122,1966

                          *** STATUS IN U.S. ***
 
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***