*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JO6415000
CHEMICAL NAME           : 3H-1,2,5-Dithiazepine-4-carboxylic acid,
                          tetrahydro-7,7-dimethyl-6-oxo-, R-
CAS REGISTRY NUMBER     : 82017-48-9
BEILSTEIN REFERENCE NO. : 5526854
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C7-H11-N-O3-S2
MOLECULAR WEIGHT        : 221.31
SYNONYMS/TRADE NAMES :
   * SA 981
   * (4R)-Tetrahydro-7,7-dimethyl-6-oxo-3H-1,2,5-dithiazepine-4-carboxylic  
   acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1809 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - dyspnea
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 29,423,1985
 
                            *** END OF RECORD ***