*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JR2125000
CHEMICAL NAME           : Dodecane
CAS REGISTRY NUMBER     : 112-40-3
BEILSTEIN REFERENCE NO. : 1697175
REFERENCE               : 4-01-00-00498 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C12-H26
MOLECULAR WEIGHT        : 170.38
WISWESSER LINE NOTATION : 12H
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Adakane 12
   * Ba 51-090453
   * Bihexyl
   * Dihexyl
   * n-Dodecan
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2672 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   37,56,1975
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11 gm/kg/22W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   9,70,1966

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 78,99,1972

   TOXICOLOGY REVIEW
   PAASAH Publication of the American Association for the Advancement of
   Science.  (Washington, DC) No.1-94, 1934-73.  Discontinued.
   Volume(issue)/page/year: 54,171,1959

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83924
       No. of Facilities: 12 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 12 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83924
       No. of Facilities: 96 (estimated)
       No. of Industries: 2
       No. of Occupations: 5
       No. of Employees: 5451 (estimated)
       No. of Female Employees: 356 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***