*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : KB0600000
CHEMICAL NAME : Ephedrine, (+)-
CAS REGISTRY NUMBER : 321-98-2
OTHER CAS REGISTRY NOS. : 4607-45-8
BEILSTEIN REFERENCE NO. : 4231286
LAST UPDATED : 199803
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C10-H15-N-O
MOLECULAR WEIGHT : 165.26
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Benzenemethanol, alpha-(1-(methylamino)ethyl)-, (S-(R*,S*))-
* (+)-Ephedrin
* (+)-Ephedrin
* (+)-Ephedrine
* d-Ephedrine
* L-(+)-Ephedrine
* (1S,2R)-Ephedrine
* (1S,2R)-(+)-Ephedrine
* (1S,2R)-Ephedrine
* (1S,2R)-(+)-Ephedrine
* (+)-(1S,2R)-Ephedrine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 255 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc.,
2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961-
Volume(issue)/page/year: 53,987,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 105 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - changes in motor activity (specific assay)
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 148,158,1965
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***