*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KC9930000
CHEMICAL NAME           : 4,7-Epoxyisoindolinium,
                          hexahydro-2,4-dimethyl-2-(2-trimethylammonioethyl)-,
                          dichloride
LAST UPDATED            : 199206
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H30-N2-O.2Cl
MOLECULAR WEIGHT        : 325.37
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-Dimethylaminoethyl-4-methyl-4,7-endoxyperhydroisoindole dimethonium  
   chloride
   * Hexahydro-2,4-dimethyl-2-(2-trimethylammonioethyl)-4,7-epoxyisoindolinium 
    dichloride
   * WY-1263
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 46,346,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 46,346,1957
 
                            *** END OF RECORD ***