*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KC9940000
CHEMICAL NAME           : 4,7-Epoxyisoindolinium,
                          hexahydro-2,4-dimethyl-2-(trimethylammonioethyl)-,
                          dichloride, theophyllinate
LAST UPDATED            : 198406
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H30-N2-O.2Cl.C7-H8-N4-O2
MOLECULAR WEIGHT        : 685.75
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * H-2 theophyllinate
   * WY-1263 theophyllinate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 145 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 47,260,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 47,260,1958
 
                            *** END OF RECORD ***