*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KT0930000
CHEMICAL NAME           : 2H-1,11c-(Epoxymethano)phenanthro(10,1-bc)pyran-5,10(
                          3H,6ah)-dione, 1,3a,4,7,7a,11,11a,11b-
                          octahydro-8,11a-beta-dimethyl-3-methylene-1-alpha,2-b
                          eta,11-beta-trihydrox y-
CAS REGISTRY NUMBER     : 981-15-7
LAST UPDATED            : 199303
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H24-O7
MOLECULAR WEIGHT        : 376.44
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ailanthone
   * Ailantone
   * Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-,  
   (1-beta,11-beta,12-alpha)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSSGAR Parassitologia.  (Parassitologia, E. Biocca, A. Corradetta, Leonardo,
   via Baglivi 5, 00161 Roma, Italy)  V.1-    1959- Volume(issue)/page/year:
   10,215,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 31400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 26,345,1991
 
                            *** END OF RECORD ***