*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KD5084000
CHEMICAL NAME           : 12,16-Epoxy-5H,12H-6,11b,16a-triazadibenzo(b,h)cyclon
                          ona(jkl)cyclopent(e)- as-indacen-5-one,
                          6,7,13,14,15,16-hexahydro-13-methoxy-12-methyl-14-(me
                          thylamino)-, hydrochloride,
                          (12-alpha,13-beta,14-beta,16-alpha)-(+)-
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C28-H26-N4-O3.Cl-H
MOLECULAR WEIGHT        : 503.04
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * AM-2282 hydrochloride
   * Staurosporin hydrochloride
   * Staurosporine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 30,275,1977
 
                            *** END OF RECORD ***